Fred Flintstone, together with his family, Wilma and Pebbles, are members of The Flintstones, an animated cartoon series, together with Barney and Betty Rubble, and their son Bamm-Bamm. His favorite phrase when he’s happy is Yabba-Dabba-Doo! Fred Flintstone’s hometown is Bedrock, a prehistoric city where dinosaurs and men live together peacefully, though dinosaurs generally fill the role of machines. For example, Fred Flintstone is a bronto crane operator, driving a brontosaurus. Every machine or appliance in the world of Fred Flintstone is powered by a dinosaur, small or big. The exception would be cars here, which are powered by the feet of its driver.

Other appearances for the Fred Flintstone character were in a Johnny Bravo episode, a Harvey Birdman Attorney At Law episode, the Grim Adventures of Billy and Mandy, in Family Guy and in The Simpsons.